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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22e9f8c065cf1bd37cc9774384aafc26130b111485ab3e119cb0a8b4cbd40a1e' 
  AND token = 'yWQi4WrwhuSqO5gN4Fb4uMTDAbWpimC3Q8mq+LfPhho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}