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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '220cd03810542ef5b26588e5f824b8158418519637673a384526c342efc65f92' 
  AND token = 'utC/80+pwSqh4wRev3CxcpphtqZlKIpbiw018/e4sNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}