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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1282b1f1d8c752b6760ffe54e78cda2bc0be44e4b4489d0ef79488e4e3979e77' 
  AND token = 'B88gm9gUR0lXf+HIKX4YBW7bTxRcIUmnZ4aoXI6TqXQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}