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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd01ddbe5f365c26cb2c27ec6c60474eb5dc6f87e4f6f1b14a2d530c4a2726e1b' 
  AND token = '8xgsInFlF+DzjkG8Dshwu3Ds4ItkzC4q1g4N8lCi3wA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}