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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aab4b8bfc397af8ae351761987461731000cf505c457cd078b5a6aa31762fed6' 
  AND token = '5txz/+ZKPmyVQUZmD6Su4bkEAPUmzDyaixu9s5KY0rA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}