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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '117baf533831d8810989242cd97b8b14e1ff6cf9728a1a42ac359a6622a7b19a' 
  AND token = 'PwLXFiLnWy6eZlKnx0rv1+qHTLR4R0XDaQ1uVSUjrKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}