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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad5d071dfcd98dc6208e933507dc4174263980d5e9db3da8cbfef30c3960d4e6' 
  AND token = 'xqaT2KIF9/k87Fup0wmz0uog7iJx1MbvUJLOQShHi9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}