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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80848ff429fe2eab6660d595f0834acf340250e765445e94a5c4f52de1554658' 
  AND token = 'aiywkBKHLnFC0pMci4HDjmsTsJXMsDoESbrVfBwBFk4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}