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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77e2a002d977603cde39cbf22715ac0dbdf809ca90b43ffa694373759e295307' 
  AND token = 'zt9RjOl1XGkhgjHH50pLoNh1ms5jAx6dNfWoUHPo4FY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}