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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9ff14be4b552513580ed93902d9ebd8c8fba985c58c2e4fd40b79b1bcfb3454' 
  AND token = 'lDL6PbLCxHxwXHPxsLW+FaCoHgz3emsiD/c3gI0c3ek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}