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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48e4b5b20f393a113910050059b1af6e0b0654919e12a454cbb0ea83029d6b80' 
  AND token = 'mVIbv3W+g3ja9DIA05DqhU22NKpRCfJUZP+voGi71OI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}