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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3448e97c3b6c0dbe6638306139cde1427cd231a6c4c1a94a86752632ad20a6b8' 
  AND token = 'NqqA8dvM86Zb+hZSpHSLzzTYk2iRgjrPt7YIjk3p4No=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}