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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '822214616eaf2df2ccb9a0106e357c9fae856f853f95938b1809812e421eaba3' 
  AND token = 'Uq+ePhUsPygf3JCk2u0hO+9FHa3OyJ/i787OajZXdSc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}