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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b4273ac5336b7279ec1f83c17ed5c5887202561e8d2a2dac4da64eff61b7a0c' 
  AND token = '+tXCJPICES/Mltl9rhpe1c/5z0Yh+S9sqRW/kTAhUrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}