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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4506079a21e5db235d3dcfd5da80b25b4f63f624f0018254c17bb0da20aca9e' 
  AND token = '6LFrhJKxfJ0LD7UVDRLdcDSKiUjOcY86LRy2oSjx3lM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}