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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '869bcbd87a711079872e79574b75f4d51d30641dc10e1e761fe70024c0810ff8' 
  AND token = 'Rs1nndox/cpyeGVSYOpGyZzRY47jr79h4WNf917ccC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}