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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5ec12edba390691bf9db2a4200eef6a02e81639577c0e817a46be5a9e79f43a' 
  AND token = 'meH9KnAvJnxsseMPsWMnXWDq25ZhgJ+RwTxI5VvGAlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}