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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6379b63102bedeb8c5c27bf147d699ed30b9c629e1ffa03ba16d20d890ec7e0e' 
  AND token = '1tFZK7IG5zoqGzhkmJIDvVa+U98eLlFZ+UDIGymE9m4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}