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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78ee95f8404ce6373f32b0b784ff64c012092bb119e027c1a091aaab4f145110' 
  AND token = '3oP/1Or4mYXxQvg4LnzQIe5zMteVcW5t3tgw3oUA6bM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}