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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8052425b8b935b5e7e74d77f68da8cd3929ad0374beed966a02f2f2ebbcf2023' 
  AND token = 'F7mAR/Z+NVhePb618p3V7DIY4Av7tnh0yu65j8mP2xs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}