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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8a446f959809d660b962e4f0537a315c9c8e74d1659ef7a5b9ef5d00209c94d' 
  AND token = 'r1ujPJtPVpeljiAog6NYl6kbhsbSsHqN0g66tJKGCtE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}