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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '303dc5c09aaa4687a3d9a58a10c1259a0251891146d18fd36f90a668a1650689' 
  AND token = '+iEPOE62KLWx8ykhkunH4DVN9evYcWFSK8c8SE01KgM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}