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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e2df6f36714bc45db85f0c3b3800b3be57bad6a331f05ffeba77ac2fb57b465' 
  AND token = 'FlKVbyLEHQFOTHRZM49NlZIMNzscdhENnCdaHKKHQRo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}