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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9925349f29a816584e1cff2c9cbdda465c4a6909d1e6ee6c58b4acb6bb038539' 
  AND token = '/gDtvoOA1xJdrf46zF90YL+baOn2osaKDZIJSMuVrao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}