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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb3978c7684fdc34122694bcf66d5345fae07877e8261cf9e163a78acd86a653' 
  AND token = 'GA7TjAkoIBUhO0GA25E21BJREcBpcAnKsM+vLT7GttE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}