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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59e8054dfb20a7603bbbd0e4e0c0d6434801072017f1167614db93035a37a202' 
  AND token = 'l6eUMDGaLqsBWYSjX9ieABqbX4LJAbZLNBXxCafIU7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}