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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d7645d9c75ffe3e53094c85e79cfffe86d0537368afa54fb5d4fb0bfe3c1d57' 
  AND token = 'C8NzrnMm58KNmStu6mqUpBW2E2gAkb6xeV8R4tMntXw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}