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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61d85a499ebcef2e01cb023df3f47d4d62631682f0fc843c68224bd7f909a714' 
  AND token = '/Np3P+pgVnJRsIxmLa3tkS3OWeTWsH30qaJmYXPFcOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}