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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '272607c68adc083817b9b1340e7da18db24be2a3e1227df3e61d49fadb0bf6bd' 
  AND token = 'hQjXoz6p7BT19uHUL85AHBAB7mZ5dozEdw4JVGzmJVo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}