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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce05b62e934a5ef858cea2063a33a220adcb6f9adc23f5fcc35d44c9728fc22d' 
  AND token = 'cqsC+J3Bz+MWOy/tflw1cxsQ0b02+8xq5xdvgc5vogo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}