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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54c079364ffd38bf80411b35e8526b824c4fcc03500dd65bec137dec5e30c500' 
  AND token = 'vMsbyt4bZNstMjTLE35XfEg33yzJlFAZcvVSAj5r/U8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}