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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e5bb866117f985b3419f9cc5a6a7b6f19fc5cdf7e209d1164eeeb98febb5610' 
  AND token = '2wBW0LOs3ejMTUkmlZAhh8lyFgnBqfvDrVkW8NZ3qzo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}