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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '250119c13d5c335e770d0c81d7158fb7537bc60248164758c0149c4fc1b5e02b' 
  AND token = 'cMfjcR98ODsE+hj6z1ymYJiPXzWH6fPJMqXUGORq+A4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}