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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f510e47510223bfb7a3fece6436f55e6bfe97dd63bdd12c21cd4a7b66cd29dd' 
  AND token = 'Ne/0t9dXEH93l2xvhRr2b0eKLHApkUSLFeD7iRzIxzM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}