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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c0dbc0c40faa9391f955531daa24df387a09347e5e20d9c789fd0a7bf0f6bee' 
  AND token = '/NwnTE+Vz4BUdc0DBLoQUwXZ0SRGHLNLjfCICfNCyNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}