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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '783f2a8c2d1b018bc8b56bcebf1bb61c7e6954a6ef2ebfe7e814aeaa50d42f8a' 
  AND token = 'NIGJ/v2s8B8UxWLjz0k7jXaFkPBF8fEp78dnlU3HWwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}