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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fd14156d7e309652dc6b46df59e8888992cc0e69a4fbf74e27340c7ef7080f3' 
  AND token = 'R5Apm4KTMcvaGDn/UQZZbyTkureiC+l4nsB6iHCN2qs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}