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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c18a9b16986f6428b08524057bd7864fbdd023ea7fcc07c01625129d367fc46' 
  AND token = '9LIUXveQL+f41AYdKugmUR4lMNW0WaNhdQ93Msi1KMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}