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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4ed6ea597ac1a9beb54de36dc4887697d81ae0e9955722f23fdd2b33c7f0f41' 
  AND token = 'C6E+Dyzr5zJogJmGzD22jFSoxrcek2L7u2LbpIPL54c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}