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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e36e9e5b19ce8fe98b39570ae00525510f46aa85bcd1e17356b7313429401f85' 
  AND token = 'BzDYz/akVBOsCFy4FT+KdrTZS3oehE7NnyiWoeNZBQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}