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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33d6f2f8e48354b436c04e8700db2a330c5378115eff41a9467d81fca37012e8' 
  AND token = 'PJgrAgc1i5n9vRcJvQ+AGS7fSSO3ImqMoGDP5al7N0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}