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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2a1e48a3f82e93ff9cd2f588b4bd2215da3da188bc6989a78ebd439cd0d83ff' 
  AND token = 'ITY4eHgPk+dcCaUDwFIivqZYd6f0/c81Gjur1qkEhU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}