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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae8b3b3151c5f5346c0b0329ea23c824df64299a24866981e001401f021ff27a' 
  AND token = 'GDY+oel9yOPrucgHWpvqsYy5ar2vvrShlIfjnl2/8Jc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}