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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a5c3560103ff1386a3d5e9acbd2ec7efde89f15491802c8f2a61942e33f5d10' 
  AND token = 'CVDr2+Wl/3X9qbzQ8XM1AJIckK/uVub8+MXMQuowBWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}