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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '310761e5c009ded2b33a1d155f99b1684dbde1ed59d9f2cb2bcf47d702ba5ba4' 
  AND token = 'Lsi96UNneR7Edvuv5TIou7JhPd1OnzFtiMFYWOSMzkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}