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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a54e4ad22298f2e8f03e1c411805a0fd221546f84c5c98352da664ceb43cdbe' 
  AND token = '57nm5ICFK3DMWF0rfaRIE28nLWIDTu8kFFRXPeUvLTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}