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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '127971dabcee0e8fc74b0b335df41f1ca3e0bad1bde476d591350bb3f643036d' 
  AND token = 'ZfOk+kl+2qQLSl6n114EXC3826ka2KvJemNLLbOix+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}