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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '578830c5df12c1ff4f0ebf0a9adc80a32b6457100508eecb1af51e530f1ad9f2' 
  AND token = 'Y4p0PWhR3ZtBmeWx4m5hmtP5UAVb6qMPs7R3jpQagX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}