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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '042718df5f9b4036f80ec2cff5d091d41978d04035ae67d1c50afcaaadf40839' 
  AND token = 'N8N0DI1ZwRRAbEDx897oanjTtsszHX85NOzvIUp/K9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}