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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3b354ecdc741d25614b4994a7318e46dcaf76244172937a11c966a27cc4178c' 
  AND token = 'hDiUUY6Sx2o8eHZJfz4dTqil2lZkP4gSnY5jXRLBpp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}